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Name: Dybkov Mykhaylo Vasyl'ovych
Company: Department of Molecular Genetics, Institute of Molecular Biology and Genetics, NAS of Ukraine,
Zabolotnogo 150, Kyiv, Ukraine,03143.
Phone: +380 44 2660729
Fax: +380 44 2660759
Fax in USA +1 501 6412144
Fax in UK + 44 870 1390256
E-mail: mdybkov@ukr.net
Personal Information
Date of Birth: July 26, 1971
Citizenship: ukrainian
Marital status: married
Education 1988-1993 Dept. General and Molecular Genetics, Fac. of Biology of Kyiv University, Kyiv, Ukraine., genetics.
Professional experience:
1992 Laboratory Technician, Department of Molecular Genetics, Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine.
1993-1995 Forensic expert, Principal bureau of forensical medicine, Ministry guards of health of Ukraine, Kyiv, Ukraine.
1993-1998 Engineer , Department of Molecular Genetics, Institute of Molecular Biology and Genetics, NAS of Ukraine, Kyiv, Ukraine.
1998-2000 Leading Engineer
2000-at present time Reseacher
Technical experience: DNA and RNA analyses (purification DNA and RNA, cloning, DNA fingerprinting and amplification and sequencies procedures)

Publication

  1. Telegeev G.D., Dybkov M.V., Karpenko O.I., Cherepenko H.J. Molecular basis Ph' leukemia and finding the way to treat them// Biopolimery i kletka, 1994, V.10, N.5, P.78-93
  2. Dybkov M.V., Telegeev G.D., Stolina M.R., Maliuta S.S. Use of the methods DNA fingerprint to study of Genetics structure and comparative analysis of strain mousses CC57W/Mv, C57Bl/6 and BALB/c. // Biopolimery i kletka,, 1995, V.11, N.1 P.66-69.[in russian].
  3. Dybkov M.V., Telegeev G.D., Druz A.F., Homenok T.O. Analysis simple of the blood by the method of DNA fingerprints (practical recommendation) // Republican centre of scientific medical information, Kyiv, 1995, 16p. [full in ukrainian, pdf] (114 kb)
  4. G.D.Telegeev, M.V.Dybkov, K.N.Kiyanitsa Optimization of conditions of obtaining the high label single strain probe based on the M13 phage // Biopolimery i kletka, 1995, V.11, N.3-4, P.104-105.
  5. Maliuta, M.V. Dybkov, G.D. Telegeev Study of DNA polymorphism of ukrainian population detected with M13 DNA. // Cytology and Genetics 1996 V30. N.1 P.31-35. [in russian and translated in english by Allerton Press]
  6. M.V. Dybkov, G.D. Telegeev, S.S. Malyuta. Spontaneous mutagenesis in mouse minisatellite for the strain CC57W/Mv. // Bioplimery i kletka, 1996, V.12, N 3 , P.61-63 [in ukrainian]
  7. K.F.Pochernayev, K.N.Kiyanitsa, G.D.Telegeev, M.V.Dybkov, S.S.Maliuta M13 phage DNA probe informativity rising at studying pig genome.// Biopolimery i kletka, 1996, V.12, N 3 , P.64-66
  8. G.D.Telegeev., M.V.Dybkov., M.V.Bozhko, N.M.Tretiak, S.S.Maliuta Molecular-biology approaches to detection of Philadelphia chromosome in patients with leukemia.// Biopolimery i kletka, 1996, V.12, N 6 , P.63-68
  9. Maliuta S.S., Telegeev G.D., Dybkov M.V., Druz A.F., Homenok T.O., Pochernayev K.F., Balacky V.M., Vazhnycha O.M. Make of use of high polymorphics DNA locus for forensic-medical expertise of liquid blood (practical recommendation)// Republican centre of scientific medical information, Kyiv, 1996 ,9p.[full in ukrainian, pdf] (96 kb)
  10. G.D.Telegeev., M.V.Dybkov., M.V.Bozhko, Demydenko D.V., S.S.Maliuta, N.M.Tretiak, Bondar M.V. Monitoring of chronical myelogenous by molecular-biology methods (practical recommendation)//Republican centre of scientific medical information, Kyiv, 1997 ,16p. [full in ukrainian,pdf] (118 kb)
  11. Telegeev G.D., Koliychuk A.N., Dybkov M.V., Maliuta S.S. Molecular basis of multiple myeloma.// Biopolimery i kletka, 1997, V.13, N.6., P.427-435.
  12. G.D.Telegeev., M.V.Dybkov., M.V.Bozhko., N.M.Tretiak., S.S.Maliuta. Molecular-biological diagnosis of blood neoplasias // Cytology and Genetics, 1998, V.32, N.1., P.71-78. [in ukrainian and translated in english by Allerton Press]
  13. G.D.Telegeev, A.N.Dubrovskaya, M.V.Dybkov. Role of BCR/ABL in leukemogenesis // Experimental Oncology, 1999, V.21, N 3-4., P.182-194 [in russian]
  14. Telegeev G.D., Dubrovska A.N., Dybkov M.V., Maliuta S.S. Mutation in bcr/abl hybrid gene as a possible factor of tumor progression during CML. //Biopolimery i kletka, 2000, V.16, N.6., P.482-486. [in ukrainian]
  15. Telegeev G.D., Dubrobskaya A.N., Dybkov M.V., Machylo V.M., Gartovska I.R. Detection of Ph'chromosome by polymerase chain reaction // Hematology and Transfusiology, 2000, V.1, N 1, P.37-40 [in ukrainian]
  16. Telegeev G.D., Dybkov M.V., Dubrovska A.N., Maliuta S.S. Deletion of the fifth exon of bcr/abl gene by acute lymphoblastic leukosis with Ph' chromosome //Biopolymery i klityna, 2001, V.17, N 4 , P.298-301 [in ukrainian]
  17. Telegeev G.D., Guseva S.A., Dubrovskaya A.N., Dybkov M.V. Tyrosine kinase inhibitor STI 571 in treatment of Ph'- leukemias // Ukrainian Journal Haematology and Transfusiology, 2001, V.3, N1, P. 14-20.[in russian]
  18. A.N.Dubrovskaya, G.D.Telegeev, M.V.Dybkov, O.S.Voloshanenko, V.V.Shved, S.S.Maliuta Mutation analysis and bacterial expression of the chimerical oncoprotein Bcr/Abl Dbl-homology domain // Biopolymery i klityna, 2002, V.18, N2 , P.96-101 [in ukrainian]
  19. M.V.Dybkov, G.D.Telegeev, A.N.Dubrovskaya, S.S. Maliuta Deletion in dbl domain of bcr/abl gene in leukemia patients with Ph' chromosome // Experimental Oncology, 2002, V.24, N2 (June) P.153-154
  20. Telegeev G.D., Dubrovska A.N., Dybkov M.V., Maliuta S.S. Influence of BCR/ABL fusion proteins on the course of Ph leukemias // Acta Biochim Polonica.– 2004.-V.51.–N.3, P.845-849.
  21. Telegeev G.D., Savov A.S., Dranitsina A.S., Dybkov M.V., Vachev B., Bezrukov V.F.SEX Identification of Gentoo penguins using PCR // Visnyk problem biologii i medycyny.– 2005.– V.3.– P. 44–47., [in russian]
  22. Ìàëþòà Ñ.Ñ., Äèáêîâ Ì.Â., Òåëåãåºâ Ã.Ä., ̳ðîøíè÷åíêî Ä.Î. Ñïîñ³á ä³àãíîñòèêè Ph’ëåéêåì³é çà äîïîìîãîþ ñïåöèô³÷íèõ ïðàéìåð³â // Äåêëàðàö³éíèé ïàòåíò íà êîðèñíó ìîäåëü UA ¹ 10385.
  23. Maliuta S.S., Telegeev G.D., Dybkov M.V., Miroshnychenko D.O., El’skaya A.V. Test-system development for Ph-leukemia diagnostics by polymerase chain reaction // Nauka ta innovacii.–2005.–V.1.–N.3, P.70–75. [in ukrainian]
  24. Ìàëþòà Ñ.Ñ., Òåëåãåºâ Ã.Ä., Äóáðîâñüêà Ã.Ì., Äèáêîâ Ì.Â., ̳ðîøíè÷åíêî Ä.Î. Âïëèâ äîäàòêîâèõ ìóòàö³é ãåíà bcr/abl íà ïåðåá³ã Ph'-ëåéêåì³é òà ¿õ âèêîðèñòàííÿ ÿê ïðîãíîñòè÷íî¿ îçíàêè // Ôóíäàìåíòàëüí³ îð³ºíòèðè íàóêè (ÔÎÍ): (Á³îëîã³ÿ ³ íàóêè ïðî Çåìëþ ³ íàâêîëèøíº ñåðåäîâèùå).– Êè¿â.– ÂÄ “Àêàäåìïåð³îäèêà”, 2005.– Ñ.48–68.
  25. E. Trakiiska, S. Bichev, G. Telegeev, M. Dybkov, V. Bezrukov, J. Jankov, A. Savov Study of Three DNA Microsatellite Markers in Pygoscelis papua Penguins (Aves: Sphenisciformes) from the Livingston Island // Acta Zoologica Bulgarica.– 2005.– V.57.–N.3, P.333–340.
  26. G.D. Telegeev, A.S. Dranitsina, M.V. Dybkov, A.S. Savov, B.Vachev, S.S. Maliuta, V.F. Bezrukov, O.Georgiev RAPD analysis of Gentoo penguins' populations // Bulgarian Antarctic Research. Life Sciences.– 2006.–V. 5.– P. 23–29.
  27. G.D. Telegeev, A.S. Dranitsina, M.V. Dybkov, E.E. Melnikova-Khablo, A.S. Savov, B.Vachev, S.S. Maliuta, V.F. Bezrukov, O. Georgiev Studying telomeres length of Gentoo penguins on the Antarctic peninsula // Bulgarian Antarctic Research. Life Sciences.– 2006.–V. 5.– P. 31–35.

Abstracts

  1. G.D. Telegeev, K.N. Kiyanitsa, M.V.Dybkov, O.I. Karpenko, S.S. Maliuta Use of DNA fingerprints to study the affects of low doses of incorporated radionuclides on the stability of genome profiles of strain mice in the generation sequence. //Abstract The Second Radiobiology Conference Kiev, 1993.
  2. M.R. Stolina, P.A. Solomko, M.V. Dybkov, G.D. Telegeev, S.S. Maliuta Elaborate of complex model system to study the genetic and molecular biology effects of chronical low dose ray //Abstr. The IV International scientific and technical conference "Chernobyl-94", Zeleny Mys, 1994., P.215-216.
  3. M.R. Stolina, P.A. Solomko, S.S. Maliuta M.V. Dybkov, G.D. Telegeev Used a model system to study genotoxic effects of low doses chronical radiation on reproducyive function of series of generation of strain mice.//Paper of The IV International scientific and technical conference "Chernobyl-94", V.2, P.322-327.
  4. M.V. Dybkov, G.D. Telegeev, S.S. Maliuta. Use of DNA fingerprint in model system to study of effects of low doses of radiation.// Abstr. The V International scientific and technical conference "Chernobyl-95"" Results of 10 years of work on liqu idation of consequences on Chernobyl Atomic Station", Zeleny Mys, 1994., P.454
  5. G.D. Telegeev, M.V.Dybkov, A.N. Koliychook, N.M.Tretiyak, S.S. Maliuta Detection of Philadelphia chromosome using molecular-biology methods // Materials of scientifically-practical conference "Present state of medical genetics in Ukraine" (1999 May 19-20, Kyiv) P.138-139
  6. G.D. Telegeev, A.N. Koliychook, M.V.Dybkov, N.M.Tretiyak, S.S. Maliuta PCR-diagnostics of multiple myeloma by using allele-specific primers // Materials of scientifically-practical conference "Present state of medical genetics in Ukraine" (1999 May 19-20, Kyiv) P.139
  7. Telegeev G.D., Dybkov M.V., Dubrovskaya A.N., Malyuta S.S. BCR/ABL mutations as tumor progression factor // Abstr. 3rd Parnas Conference Mechanism of cellular signal transduction and communication, October 14-18, 2000, Lviv., P.143
  8. Telegeev G.D., Dybkov M.V., Dubrovskaya A.N., Malyuta S.S. A second mutaion of bcr/abl oncogene as possible factors of tumour progression // Abstr. Second congress of oncologist of country of UIS, 23-26 May, Kyiv, Ukraine, P.207
  9. Dybkov M.V. Mutation of bcr/abl oncogene in patient with Ph' leukemias. //Abstr. Conference for students, PhD students and young scientists on molecular biology and genetics, September 20-22, 2001, Kyiv, Ukraine, P.138
  10. Telegeev G.D., Dubrovskaya A.N., Dybkov M.V., Malyuta S.S. Changing of cytoskelet as a marker of tumor progession by chronic lymphoblastic leukemia // Abstr. IV congress of gematologist and transfusiologist of Ukraine, 16-18 May 2001, Kyiv, Ukraine, P.92
  11. Telegeev G.D., Dybkov M.V., Dubrovskaya A.N., Malyuta S.S. Delection of bcr/abl gene by acute lymphoblastic leukemia with Philadelphia chromosome// Abstr. IV congress of gematologist and transfusiologist of Ukraine, 16-18 May 2001, Kyiv, Ukraine, P.93
  12. Gartovskaya I.R., Nikolskaya N.A., Stelmakh E.A., Telegeev G.D., Dybkov M.V., Dubrovskaya A.N. Experience of use the alpha-2beta-interferon in treatment of a chronic myeloid leukemia // Abstr. IV congress of gematologist and transfusiologist of Ukraine, 16-18 May 2001, Kyiv, Ukraine, P.93
  13. A.N.Dubrovska, G.D.Telegeev, M.V.Dybkov, S.S.Maliuta Working out immunochemical test-system for detection p210 BCR-ABL protein at patients with chronical myelogenous leukemia and acute lymphoblastic leukemia // Materials of the III scientifically-practical conference "Problems of oncogenetics and applied aspects" (2002 May 23-24, Kyiv) P. 18
  14. G.D.Telegeev, M.V.Dybkov, A.N.Dubrovska, S.S.Maliuta Deletion in dbl region of bcr/abl gene in Ph'-positive leukemias // Materials of the III scientifically-practical conference "Problems of oncogenetics and applied aspects" (2002 May 23-24, Kyiv) P. 47
  15. Volkova I., Dubrovskaya A., Telegeev G.D., Dybkov M.V. Cloning and bacterial expression dbl-homology domain of fusion BCR/ABL protein // 6th Puschino School-Conference young scientist "Biology - science of XXI century" (May 20-24, 2002, Puschino). T.1, P. 227-228.
  16. Telegeev G.D., Dybkov M.V., Dubrovska A.N., Maliuta S.S. Influence of Bcr/Abl fusion proteins on course of Ph' leukemias // Abstr. 4rd Parnas Conference Molecular mechanism of cell activation: biological signals and their target enzymes, September 15-17, 2002, Wroclaw., P.22
  17. M.V.Dybkov, G.D.Telegeev, A.M.Dubrovska, S.S.Maliuta Molecular-biological and biochemical aspects of chronical myelogenous leukemia / Abstr. of The VIII Ukranian Biochemical Congress (Chernivcy, October 1-3, 2002, Ukraine) / The Ukrainian Biochemistry Journal, 2002, V.74 N4b (part 2), P.6.
  18. Miroshnichenko D.A., Dybkov M.V., Telegeev G.D. Cloning and bacterial expression of ABL/BCR GAP region in chronic myeloid leukemia // Abstr. of Conference for young Scientists, PhD Students and Students on Molecular Biology and Genetics, September 25-27, 2003 Kyiv, Ukraine, P. 182
  19. Volkova I., Dybkov M., Dubrovska A., Telegeev G.D. Testing of biological activity of DBL-PT drug on K562 cells // Abstr. of Conference for young Scientists, PhD Students and Students on Molecular Biology and Genetics, September 25-27, 2003 Kyiv, Ukraine, P. 272
  20. D.A. Miroshnichenko, I.A. Volkova, E.I. Zakharchenko, M.V. Dybkov, G.D. Telegeev Role of abl/abr gene in pathogenesis of Ph leukemias // Abstr. of The VI Conference for Young Oncologist "Modern problems of experimental and clinical oncology, December 4-5, 2003 Kyiv, Ukraine, P. 40
  21. Telegeev G.D., Dybkov M.V., Dubrovska A.M., Miroshnichenko D.A., Maliuta S.S. Receiving of polyclonal antibodies for different region of hybrid proteins at Ph-leukemias and using them for diagnostics and studing of pathogenesis of the illness // Abstr. of the First (Inagural) Ukrainian Congress for Cell Biology (25-28 April 2004., Lviv), P.123.
  22. M.V. Dybkov, G.D. Telegeev, A.S. Legeyda, V.F. Bezrukov. DNA markers for studying penguin's populations at Antarctic Peninsula // Abstr. of the Second Ukrainian Antarctic Meeting "Antarctic Peninsula: key region for environment change study" 2UAM2004 (June 22-24, 2004 Kyiv, Ukraine), P.167
  23. A.S. Savov, G.D. Telegeev, S.N. Bichev, E.S. Trakiiska, M.V. Dybkov, R. Metcheva, B. Vachev, A.S. Legeyda, V.F. Bezrukov Sex identification of Gentoo Penguins using PCR with specific primers // Abstr. of the Second Ukrainian Antarctic Meeting "Antarctic Peninsula: key region for environment change study" 2UAM2004 (June 22-24, 2004 Kyiv, Ukraine), P.166
  24. G.D. Telegeev, A.S. Legeyda, M.V. Dybkov, A.S.Savov, B.Vachev, V.F. Bezrukov Molecular-biological analysis of Gentoo penguins at Antarctic Peninsula. //Abst. of XXVII Symposium on Polar Biology, December 2-3, 2004, Japan P. PM-34
  25. 45. Telegeev Gennady D., Alevtina S. Legeyda, Mykhaylo V. Dybkov, Alexey S. Savov, Boyko Vachev, Volodymyr F. Bezrukov. DNA markers for studing Gentoo Penguins at Antarctic Peninsula // Abstr. of the 22nd International Polar Meeting German Society of Polar Research September 18- 24, 2005 Jena, Germany, P.137–138
  26. A. Dranitsina, G. Telegeev, M. Dybkov, V. Bezrukov, A.Savov, B.Vachev RAPD-analysis of Gentoo, Chinstrep and Adelie Penguins at Antarctic Peninsula // Abstr. of the II International INTAS Workshop “Comparative population and monitoring research on Gentoo penguins (Pygoscelis papua) in Antarctica”, 08.07–11.07.2005 Sofia, Bulgaria., P.9.
  27. M. Dybkov, G. Telegeev, A. Dranitsina, V. Bezrukov, A.Savov, B.Vachev The multilocus DNA fingerprinting of Pigoscelis papua, Pigoscelis adeliae and Pigoscelis antarctica penguins // Abstr. of the II International INTAS Workshop “Comparative population and monitoring research on Gentoo penguins (Pygoscelis papua) in Antarctica”, 08.07–11.07.2005 Sofia, Bulgaria., P.12.
  28. G. Telegeev, A. Dranitsina, M. Dybkov, E. Melnikova-Khablo Studying of telomeres lenth of Gentoo Penguins at Antarctic Peninsula // Abstr. of the II International INTAS Workshop “Comparative population and monitoring research on Gentoo penguins (Pygoscelis papua) in Antarctica”, 08.07–11.07.2005 Sofia, Bulgaria., P.13.
  29. G. D. Telegeev, A. S. Dranitsina, M.V. Dybkov, S. S. Maliuta,V.F. Bezrukov Genetic diversity in Gentoo Penguins // Abstracts of XXVIII Symposium on Polar Biology (2005 December 8 and 9, Tokyo, Japan), PM-24, P.54.
  30. A.S. Drantsina, G.D. Telegeev, M.V. Dybkov, I.N.Chumachenko, V.F. Bezrukov Molecular-biological markers for analysis of genetic diversity in Gentoo penguin populations // Abstracts of III International Conference "SCIENTIFIC INVESTIGATIONS IN ANTARCTICA" Kyiv, Ukraine 19 May -1 June 1006

References available on request.



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